Research
A low-dose neuromodulator lift for under-eye hollows, measured in millimeters
A 35-patient 3D-imaging study separates the real lift from the short-lived volume bump.
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Dalphene Labs
Medical aesthetics
Archive
Every published Dalphene Labs brief, grouped by the four live sections.
35 briefs
Research
13 briefsResearch
Microfocused ultrasound plus microneedle RF, head to head on the same face
A 26-patient split-face trial shows where stacking two devices actually pays off.
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Doubling your PDO thread count does not double the lift
A randomized trial of 3 versus 6 threads per hemiface, measured by 3D imaging.
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You may not need to customize glabellar injection points to contraction pattern
A 42-patient review tests whether the patient's frown pattern predicts the result.
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Masseter slimming peaks at 12 weeks, and chewing holds steady
A 24-patient prospective study tracks both jawline volume and bite function.
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A two-plane tear-trough technique matched to filler stiffness
A small case series layers high- and low-G-prime fillers to cut lumpiness and Tyndall.
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Four Neurotoxins, Same Peak: Onset and Duration Were the Only Real Differences
A double-blind RCT measured glabellar strain by 3D photogrammetry across four toxins. They split on onset and on the 6-month tail, not at peak.
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Ultrasound-Guided Hyaluronidase Reversed Filler Ischemia on a Fraction of the Dose
Three imaged cases plus a systematic review of 83 cases argue for targeting the occluded vessel instead of flooding the region.
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Cold-Crosslinked HA Held Nasolabial Correction Better Than Restylane-L at 6 and 12 Months
A split-face RCT against Restylane-L in the nasolabial fold, read out to 12 months.
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PLLA vs CaHA: A Durability Gap of Roughly Two Years vs One
A PRISMA review of 14 studies puts numbers on the durability difference between the two biostimulators.
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Skinvive Added to Crow's-Feet Botox Improved the Lines the Toxin Missed
A split-face crow's-feet RCT tested whether an HA booster adds anything to toxin. It does, just not where you would expect.
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Under-Eye Rejuvenation: When Polynucleotides Beat Reflexive HA Filler
A narrative review on choosing between volume and skin quality in the high-risk periorbital zone.
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Polynucleotides vs HA filler for the under-eye, reviewed
An evidence review lands on case selection, not a winner.
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6 briefsCompliance
Japan regulator warns on subscription billing in online beauty consults
Auto-refills shipping a year of product with no physician reassessment.
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FDA sends 25 warning letters over compounded GLP-1 marketing
Third enforcement wave in under a year, and the exposure is in your marketing copy.
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Filler death of Estée Lauder executive ruled an accident
A high-profile filler fatality, ruled an accident, that comes down to intravascular injection.
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South Korea bans 'insurance-eligible' ads for non-covered cosmetic care
Penalties for patient-inducing ads roughly triple, to a six-month license suspension.
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South Korea legalizes telemedicine for foreign patients
Remote first-time consults for foreign patients, aimed straight at cosmetic medical tourism.
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Georgia bans paid 'ghost director' deals at med spas
The board will judge the practical reality of oversight, not the paperwork.
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10 briefsIndustry
Medytox wins China approval for Neuramis filler, launching as Filux
A Korean HA filler clears the NMPA, one more step in Korean supply pushing into China.
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Health Canada clears Boey, the first serotype-E aesthetic neurotoxin
A short-acting, fast-onset toxin built on a brand new class gets its first green light anywhere.
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Medytox unit wins Korean approval for animal-free 200-unit toxin
A higher-dose, animal-component-free Korean toxin signals where lower-cost supply is heading.
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VIG Partners builds new Korean aesthetics major, LYV Sciences
A private-equity roll-up creates a full-portfolio Korean supplier of filler, biostimulator and toxin, aimed at the US and Europe.
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Japan's aesthetics market: 1.22 million users, only 2% penetration
631 billion yen, growing, and chains take roughly half of what converts.
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Korea's filler and device exports hit fresh record in May 2026
Filler and energy-device shipments surged into the US and Brazil as derm-led medical tourism set its own record.
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FDA clears SKINVIVE for neck lines, a first for HA
Allergan's microdroplet HA picks up a second indication, this time on-label for the neck.
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FDA approves Obagi saypha ChIQ, its second US filler
A cheek and midface HA gel builds out Obagi's injectable line, with the ALOHA data hinting at the real play.
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Waldencast sells Obagi Medical to Bridgepoint for up to $460M
A practitioner-distributed skincare and filler brand changes private-equity hands as beauty and medical aesthetics keep converging.
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Foreign patients spent $8.3 billion on Korean medical services in 2025
Dermatology, not surgery, drives a record 2.01 million foreign patients.
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6 briefsNews
Ozempic face is pulling Gen X to surgery a decade early
GLP-1 facial hollowing is moving a high-spend injectable cohort toward permanent surgery.
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Dermatologic Surgery devotes special issue to GLP-1 aesthetic fallout
The ASDS journal moves post-weight-loss facial change into formal clinical discussion.
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Korea's anti-aging derm society adds a 'skin longevity' track
A new longevity session and a first-ever controversy debate at KSAAD's summer meeting.
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Korea to bar non-specialist GPs from 'Dermatology' clinic signs
New and relocated clinics only, and the window-ad loophole stays open.
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UK approves first oral GLP-1 weight-loss tablet
Needle-free access widens the population feeding post-weight-loss aesthetic demand.
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Allergan study: deeper consultations drive patients to treat more areas
A vendor consumer report ties consultation depth to larger treatment plans.
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